Research in Primary Care (NHS)
Research is a core part of the NHS. It enables the NHS to improve the current and future health of the people it serves.
The Francis Grove surgery is a research site and we have been involved in patient research for the past 5 years.
The practice will decide whether to proceed with a project if it is appropriate for the study, and who may wish to sign up. Patients are normally seen in the surgery by our practice nurses or by a research nurse. Patient information is kept in the strictest of confidence. Patient consent is required and the data gathered is for NHS research only.
Alongside Research conducted in partnership with the National Institute of Health Research we also work with an organisation called Optimum Patient Care (OPC) Clinical and Research Services. Please see the poster
for more information on their services.
Clinical Research at Francis Grove Surgery
Francis Grove Surgery is proud to be a Research Ready Accredited Practice. We work collaboratively with the NIHR Clinical Research Network which is the Research arm of the NHS.
Clinical Research is very important to improve care, treatments and ultimately patients’ quality of life.
If you are a patient at the, you may receive invitation letters to ask if you wish to take part in a research study. Joining in a research study is completely voluntary.
If you do not wish to take part in research studies then please let the practice know.
To find out more information about clinical research studies please visit:
Current Research at Francis Grove Surgery
We are participating in or recruiting for the following studies:
- ARCHIE: www.archiestudy.com
ARCHIE is a seasonal study so we will only be actively recruiting during the Flu season.
Why are they doing the ARCHIE study?
They would like to find out whether giving an antibiotic called co-amoxiclav to ‘at risk’ children aged 6 months to 12 years early on when they have flu or flu-like illness might:
1. Help stop them from developing bacterial infections and becoming more unwell.
2. Help them get better more quickly.
3. Affect how well antibiotics work against similar infections in future. ‘At risk’ children with a long-term medical condition or disability are particularly prone to developing bacterial infections if they get flu or a flu-like illness.
Francis Grove surgery only have a total of 48 children who meet the criteria for this study and they will be asked on booking an appointment if they have cold/flu symptoms and will then be booked in with the GP who is leading on the study whenever possible so this can be discussed with the patients parent if appropriate. Please go on to their website for more information.
- RESIST: Understanding the role of depression in heart disease
People who suffer with depression are at greater risk of heart problems. It is not yet understood why. A growing number of scientists believe that depression and heart disease may be influenced by the immune system. In this study, they will compare the blood of people with depression to people who do not have depression. By taking part you will help to increase the knowledge of what causes people to be more susceptible to depression and heart disease. We hope that in the future this knowledge may lead to the development of better treatments and improved prevention of these illnesses.
- Age: 18-74 (inclusive)
- Gender: both female and male
- Presenting with depressive symptoms
- Other psychiatric disorders: psychosis, schizophrenia, bipolar disorder, mania, hypomania, dementia, and eating disorder
- Unable to read, understand and/or complete questionnaires
- Pregnant or lactating women
- Alcohol/drug dependence
- Significant physical illnesses (e.g. autoimmune diseases, hypertension, cancer, hematological, cardiovascular, endocrine, pulmonary, renal, hepatic)
If you are interested in participating in this study please ask your GP about it a your next visit.
- LACE: Leucine and ACE inhibitors as therapies for sarcopenia: a two by two factorial randomised placebo controlled trial
Sarcopenia is a major contributor to loss of mobility, falls, loss of independence, morbidity and mortality amongst older people. Resistance exercise training is the only intervention currently known to be effective in preventing and reversing sarcopenia. However, many older people may be unable or unwilling to undertake regular exercise of this sort. Leucine supplementation has been shown to counter resistance to muscle protein synthesis in older people. Previous research by the study team has shown that treatment with the ACE inhibitor, perindopril, improved exercise capacity to the same extent as 6 months of exercise training in a group of older people with mobility problems. The LACE study will investigate the effect of leucine and perindopril on muscle mass and function in older adults with sarcopenia.
Patients will be invited by letter if they are eligible
Given the success of the pedometer intervention at increasing individual’s physical activity at 12 months we are now developing the intervention further. Firstly, we are looking to include online support. Secondly, we want to test out different recruitment approaches, to see which are most feasible and acceptable to primary care patients, health care practitioners and practices.
We are looking to move our findings from research into routine care with a small number of patients. We are only looking to recruit about 20 participants over about four months via the NHS Health Check process predominantly.
Researchers (Via Clinical staff at our Surgery) provide packs with instructions about the effective 12-week PACE-UP walking programme and a pedometer and details for contacting us for telephone or online support.
If you have low levels of activity and are interested in taking part, please ask Nurse Sarah Buttinger for more information.